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Get Ready for Dystonia Zoo Days

Mark your calendars and get ready for these 2025 Dystonia Zoo Days events! Be sure to sign up by the T-Shirt registration deadline so everyone can see that you are a part of the “Zoo Crew” at your local Dystonia Zoo Day! Visit our events page to see a full listing of upcoming community events.

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Dystonia News

Latest Developments

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Current Dystonia Research Investigations

The Dystonia Medical Research Foundation (DMRF) prides itself on a long history of supporting and stimulating dystonia research

Neurosurgery in Pediatric Dystonia: A multimodal analysis of complex decisions

Dr. Piazza will research how families make informed decisions about deep brain stimulation (DBS) surgery for children with dystonia by addressing two key gaps: understanding how families weigh the benefits and risks of DBS and comparing its long-term effectiveness and costs to standard medical care. Ultimately, the research will provide better support for families, guiding them through complex decisions about their child's care.
Martin Piazza, MDUniversity of Pittsburgh, Pittsburgh, PA
A Role for Striatal Somatostatin Interneurons in Hyperkinetic Movement Disorders

Dr. Scarduzio seeks to further explain why somatostatin-expressing interneurons (SOMs) found in certain brain circuits in the striatum become highly active when dystonia-like symptoms are induced. By testing ways to control these cells, she hopes to better understand how to treat movement disorders like dystonia.
Mariangela Scarduzio, PhDUniversity of Alabama at Birmingham, Birmingham, AL
Striatal Neural Correlates of Overuse Dystonia

Dr. Silva aims to introduce a new mouse model where repetitive training of a skilled task triggers dystonia, hoping to better understand the brain circuits involved and test deep brain stimulation (DBS) as a treatment. By studying brain activity during dystonia development in the new mouse model, this project hopes will shed insights into the condition’s mechanisms and uncover new pathways for therapeutic development.
Joaquim Alves da Silva, MD, PhDChampalimaud Foundation, Lisbon, Portugal
More Research Projects

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