Since the first year of operations, the DMRF has supported research investigations related to the causes, mechanisms, prevention, and treatment of all forms of dystonia. DMRF’s major grant funding mechanism is based on requests for applications focusing on specific research areas informed by the Medical & Scientific Advisory Council and scientific meetings and workshops. The DMRF simultaneously remains open to new investigator-initiated ideas and approaches, which are accepted throughout the year.
The DMRF also collaborates with investigators and research entities to address a specific question or knowledge gap through research contracts.
Current Funding Opportunities
The Dystonia Medical Research Foundation (DMRF) is seeking applications for a study on myoclonus-dystonia (M-D) that will address the most significant and immediate needs of the M-D research field.
Myoclonus-dystonia is a rare movement disorder characterized by a combination of rapid jerking movements, myoclonus and/or sustained twisting and contractions that result in abnormal dystonic postures. Ethanol appears to temporarily alleviate some of the symptoms in M-D. However, ethanol’s detrimental effects preclude its use as an accepted treatment. It is well-known that ethanol consumption affects locomotor and sensorimotor activities by acting on inhibitory systems of the brain. Although the precise mechanism of its action in myoclonus remains to be elucidated, this may provide a key to understanding the pathophysiology of M-D.
Innovative research proposals to investigate the pathophysiology of M-D are suitable. Projects that attempt to clarify brain mechanisms responsible for ethanol action in M-D are particularly encouraged. This can include studies in suitable animal models of M-D.
Conditions of Award
Individuals with appropriate scientific credentials employed by a non-profit or for-profit institution, domestic or foreign are eligible to apply. The award will support researchers or research groups with one or multiple principal investigators for a budget not exceeding a total of $150,000 that could be spent over 1 or 2 years. A one-page letter of intent is required and should be submitted electronically to DMRF by January 15, 2020. It should include a descriptive title and brief summary of proposed research, as well as names and affiliations of participating researchers. The deadline for applications is February 24, 2020.
Address for Inquiries and Submissions
Jody Roosevelt at firstname.lastname@example.org or 312-447-5150
This funding opportunity has been made possible through a generous gift to the DMRF from the Brown Family Foundation. DMRF’s commitment to support the award is conditional on the availability of funds.