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Dystonia Medical Research Foundation Announces 2025 Grant and Fellowship Recipients to Propel Dystonia Research

The Dystonia Medical Research Foundation (DMRF), a leading non-profit organization dedicated to funding research to find a cure for dystonia, is proud to announce its 2025 grant and fellowship recipients. This year, the DMRF awarded six grants and fellowships for basic and clinical dystonia research projects. These grants and fellowships will support scientists investigating the underlying causes and mechanisms of dystonia and developing new treatment strategies.

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Current Dystonia Research Investigations

The Dystonia Medical Research Foundation (DMRF) prides itself on a long history of supporting and stimulating dystonia research

Neurosurgery in Pediatric Dystonia: A multimodal analysis of complex decisions

Dr. Piazza will research how families make informed decisions about deep brain stimulation (DBS) surgery for children with dystonia by addressing two key gaps: understanding how families weigh the benefits and risks of DBS and comparing its long-term effectiveness and costs to standard medical care. Ultimately, the research will provide better support for families, guiding them through complex decisions about their child's care.
Martin Piazza, MDUniversity of Pittsburgh, Pittsburgh, PA
A Role for Striatal Somatostatin Interneurons in Hyperkinetic Movement Disorders

Dr. Scarduzio seeks to further explain why somatostatin-expressing interneurons (SOMs) found in certain brain circuits in the striatum become highly active when dystonia-like symptoms are induced. By testing ways to control these cells, she hopes to better understand how to treat movement disorders like dystonia.
Mariangela Scarduzio, PhDUniversity of Alabama at Birmingham, Birmingham, AL
Striatal Neural Correlates of Overuse Dystonia

Dr. Silva aims to introduce a new mouse model where repetitive training of a skilled task triggers dystonia, hoping to better understand the brain circuits involved and test deep brain stimulation (DBS) as a treatment. By studying brain activity during dystonia development in the new mouse model, this project hopes will shed insights into the condition’s mechanisms and uncover new pathways for therapeutic development.
Joaquim Alves da Silva, MD, PhDChampalimaud Foundation, Lisbon, Portugal
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